Staphylococcus aureus, methicillin sensitive

Antibiotic
% Susceptible
 
Antibiotic
% Susceptible
Ampicillin
-
   Imipenem
+
Azithromycin
51
   Levofloxacin
92
Aztreonam
-
   Meropenem
+
Cefazolin
100
   Moxifloxacin
97
Cefepime
+
   Nitrofurantoin
&
Ceftazidime
+/-
   Oxacillin/Naf
100
Ceftriaxone
95
   Penicillin
6
Cefuroxime
+
   Piperacillin
-
Ciprofloxacin
85
   Piperacillin/tazo
+
Clarithromycin
+
   Ticarcillin/Clav
+
Clindamycin
78
   Tobramycin
+
Doxycycline
97
   TMP/SMX
100
Erythromycin
68
   Unasyn/Aug
99
Gentamicin
+
   Vancomycin
100
 
   

Comments:   Fluoroquinolone use as first line agents against Staph aureus is discouraged.

 

Numeric data represent local susceptibility data.
(+) = usually effective or >60% susceptible; (+/-) = clinical trials lacking or 30-60% susceptible; (-) = not effective clinically or <30% susceptible - Adapted with permission from The Sanford Guide to Antimicrobial Therapy 2007
(*) Local (non-Sanford Guide) opinion
(S) = synergistic with penicillin/ampicillin;
(&) nitrofurantoin only useful for lower tract urinary tract infections